Decline in clinical status guidelines
These changes in clinical variables are listed in order of their likelihood to predict poor survival, the most predictive first and the least predictive last. No specific number of variables must be met, but fewer of those listed first (more predictive) and more of those listed last (least predictive) would be expected to predict longevity of six months or less.
Progression of disease as documented by worsening clinical status, symptoms, signs and laboratory results
Clinical Status
Recurrent or intractable infections such as pneumonia, sepsis or upper urinary tract.
Progressive inanition as documented by
• Weight loss not due to reversible causes such as depression or use of diuretics
• Decreasing anthropomorphic measurements (mid-arm circumference, abdominal girth), not due to reversible causes such as depression or use of diuretics
• Decreasing serum albumen or cholesterol
Dysphagia leading to recurrent aspiration and/or inadequate oral intake documented by decreasing food portion consumption.
Symptoms
Dyspnea with increasing respiratory rate
Cough, intractable
Nausea/vomiting poorly responsive to treatment
Diarrhea, intractable
Pain requiring increasing doses of major analgesics more than briefly.
Signs
Decline in systolic blood pressure to below 90 or progressive postural hypotension
Ascites
Venous, arterial or lymphatic obstruction due to local progression or metastatic disease
Edema
Pleural / pericardial effusion
Weakness
Change in level of consciousness
Laboratory
Increasing pCO2 or decreasing pO2 or decreasing SaO2
Increasing calcium, creatinine or liver function studies
Increasing tumor markers (e.g. CEA, PSA)
Progressively decreasing or increasing serum sodium or increasing serum potassium
Decline in Karnofsky Performance Status (KPS) or Palliative Performance Score (PPS) from <70% due to progression of disease.
Increasing emergency room visits, hospitalizations, or physician’s visits related to hospice primary diagnosis
Progressive decline in Functional Assessment Staging (FAST) for dementia (from ≥7A on the FAST)
Progression to dependence on assistance with additional activities of daily living
Progressive stage 3-4 pressure ulcers in spite of optimal care
Both guidelines should be met
Physiologic impairment of functional status as demonstrated by declining Karnofsky Performance Status (KPS) Palliative Performance Score (PPS)
Dependence on assistance for two or more activities of daily living (ADLs)
• Feeding
• Ambulation
• Continence
• Transfer
• Bathing
• Dressing
Note: The word “should” in the disease specific guidelines means that on medical review the guideline so identified will be given great weight in making a coverage determination. It does not mean, however, that meeting the guideline is obligatory.
Co-Morbidities
Although not the primary hospice diagnosis, the presence of disease such as the following, the severity of which is likely to contribute to a life expectancy of six months or less, should be considered in determining hospice eligibility.
Chronic obstructive pulmonary disease
Congestive heart failure
Ischemic heart disease
Diabetes mellitus
Neurologic disease (CVA, ALS, MS, Parkinson’s)
Renal failure
Liver Disease
Neoplasia
Acquired immune deficiency syndrome
Dementia
Cancer
Disease with distant metastases at presentation OR
Progression from an earlier stage of disease to metastatic disease with either:
1. a continued decline in spite of therapy
2. patient declines further disease directed therapy
Note: Certain cancers with poor prognoses (e.g. small cell lung cancer, brain cancer and pancreatic cancer) may be hospice eligible without fulfilling the other criteria in this section.
Amyotrophic Lateral Sclerosis
Patients tend to have a constant overall rate of decline, whether rapid or slow:
Critically Impaired Breathing Capacity occurring over the past 12 months with all of the following:
a. Dyspnea at rest
b. Supplemental O2 at rest
c. No ventilator or ventilator only for comfort. A vital capacity < 30% is supportive, if available or
Rapid Progression and Critical Nutritional Impairment with all of the following in the past 12 months:
a. Bed-bound
b. Barely or unintelligible speech
c. Pureed diet
d. Major assist in all ADLs
e. Insufficient oral intake
f. Continuing weight loss
g. Absence of artificial feeding methods, except to relieve hunger
Rapid Progression and Life Threatening Complications with one of the following in the past 12 months:
a. Recurrent aspiration pneumonia
b. Upper UTI
c. Sepsis
d. Recurrent fever in spite of antibiotics
e. Stage 3/4 decubitus ulcers
Alzheimer’s disease and related disorders
Dependent in 3/6 ADLs
Urinary or fecal incontinence (intermittent or constant)
FAST 7A- Unable to speak limited to approximately ≤ 6 intelligible different words in an average day or in the course of an intensive interview.
One of the following in the past 12 Months:
a. Aspiration pneumonia
b. UTI
c. Septicemia
d. Stage 3/4 decubitus ulcers
e. Recurrent fever on antibiotics
f. Weight loss > 10% in past six months/ albumin < 3.0
The FAST scale is used to determine the functional and mental status of a patient with Alzheimer’s. To be hospice appropriate, a patient with Alzheimer’s Disease or related disorders must have a FAST of 7A or greater. The presence of co-morbid conditions (Heart disease, Diabetes, COPD, CVA, etc.) will support eligibility.
Functional Assessment Staging Scale (FAST)
No difficulty either subjectively or objectively
Complains of forgetting location of objects. Subjective work difficulties
Decreased job functioning evident to co-workers. Difficulty in traveling to new locations, Decreased organizational capacity
Decreased ability to perform complex tasks (planning dinner for guests, handling personal finances, forgetting to pay bills)
Requires assistance in choosing proper clothing to wear for the day, season or occasion, (e.g. pt may wear the same clothing repeatedly)
Occasionally or more frequently over the past few weeks:
a. Improperly putting on clothes without assistance or cueing
b. Unable to bathe properly (not able to choose proper water temp)
c. Inability to handle mechanics of toileting (e.g., forget to flush the toilet, does not wipe properly or properly dispose of toilet tissue)
d. Urinary incontinence
e. Fecal incontinence
a. Unable to speak limited to approximately ≤ 6 intelligible different words in an average day or in the course of an intensive interview.
b. Speech is limited to the use of a single intelligible word in an average day or in the course of an intensive interview
c. Ambulatory ability is lost (cannot walk without personal assistance or the use of assistive devices)
d. Cannot sit up without assistance (e.g., the individual will fall over if there are not lateral rests [arms] on the chair.)
e. Loss of ability to smile.
f. Loss of ability to hold up head independently
Stroke/Coma
The medical criteria listed below would support a terminal prognosis for individuals with a diagnosis of stroke. Medical criteria 1 and 2 are important indicators of functional and nutritional status respectively, and would thus support a terminal prognosis if met.
PPS equal to or less than 40%
Inability to maintain hydration and caloric intake with one of the following:
a. Weight loss greater than 10% during the previous 6 months or 7.5% in the last 3 months
b. Serum albumin less than 2.5
c. Current history of pulmonary aspiration not responsive to speech therapy intervention
d. Dysphagia that prevents the patient from receiving adequate food and fluid necessary to sustain life in a patient who does not receive artificial nutrition or hydration
e. Sequential caloric counts documenting inadequate calorie and fluid intake
Supportive documentation:
• Aspiration pneumonia
• UTIdfd
• Sepsis
• Decubitus ulcers stage 3-4
• Recurrent fever despite antibiotics
The medical criteria listed below would support a terminal prognosis for individuals with a diagnosis of coma (any etiology):
Comatose patients with any three of the following on day three of coma:
Abnormal brain stem response
Absent verbal response
Absent withdrawal response to pain
Heart Disease
The medical criteria listed below would support a terminal prognosis for individuals with a diagnosis of heart disease. Medical criteria 1 and 2 are important indications of the severity of heart disease and would thus support a terminal prognosis if met:
Supportive documentation:
• Orthopnea
• Paroxysmal nocturnal dyspn
• Dependent pitting edema
• Syncope
• Weakness
• Chest pain
• Diaphoresis
• Cachexia
• Jugular vein distention
• Rales
• Liver Enlargement
• History of cardiac arrest or resuscitation
• Arrhythmias
• Brain embolism from cardiac origin (CVA)
• Significant congestive heart failure may be documented by an ejection fraction of ≤20%, but is not required if not available.
Pulmonary Disease
Patients will be considered to be in the terminal stage of pulmonary disease (life expectancy of six months or less) if they meet the following criteria.
Supportive documentation:
• Cor pulmonale
• Weight loss, 10% in past six months
• HR > 100/min at rest
Liver Disease
Patients will be considered to be in the terminal stage of liver disease (life expectancy of six months or less) if they meet the following criteria:
a. Refractory ascites or non-compliance
b. Spontaneous bacterial peritonitis
c. Hepato-renal syndrome
d. Refractory encephalopathy or non-compliance
e. Recurrent esophageal variceal bleeding despite treatment
Supportive documentation:
• Weight loss > 10%
• Muscle wasting/loss of strength
• Continued alcohol consumption
• Hepatocellular cancer
• HBsAg positive
• Hepatitis C refractory to treatment
Renal Disease
Patients will be considered to be in the terminal stage of renal disease (life expectancy of six months or less) if they meet the following criteria.
Acute renal failure
Supportive documentation
• Mechanical ventilation
• Malignancy (other organ system)
• Chronic lung disease
• Advanced cardiac disease
• Advanced liver disease
• Sepsis
• Immunosuppression/AIDS
• Albumin
• Cachexia
• Platelet count <25,000
• Disseminated intravascular coagulation
• Gastrointestinal bleeding
Chronic renal failure
Supportive documentation
• Uremia
• Oliguria (
• Intractable hyperkalemia (>7.0) not responsive to treatment
• Uremic pericarditis
• Hepatorenal syndrome
• Intractable fluid overload, not responsive to treatment
HIV Disease
Patients will be considered to be in the terminal stage the illness (life expectancy of six months or less) if they meet the following criteria (1 and 2 must be present)
Supportive documentation
• Chronic persistent diarrhea for one year
• Persistent serum albumin <2.5
• Concomitant, active substance abuse
• Age >50 years
• Absence of antiretroviral, chemotherapeutic and prophylactic drug therapy
• Advance AIDS dementia complex
• Toxoplasmosis
• Congestive heart failure
Other Terminal Illness
Observable and documented deterioration in overall clinical condition in the past 6 months as evidenced by any of the following:
Our team members do not view the care we provide as work, but rather a ministry in which we can serve and better the lives of those around us. At Southern Grace, we don’t focus on death and dying, but rather on life and living.